Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c‐MYC

Overexpression of ferritin heavy chain (FTH1) often associates with good prognosis in breast cancer (BCa), particularly in the triple‐negative subtype (triple‐negative breast cancer). However, the mechanism by which FTH1 exerts its possible tumor suppressor effects in BCa is not known. Here, we exam...

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Hauptverfasser: Amjad Ali, Jasmin Shafarin, Rola Abu Jabal, Nour Aljabi, Mohamad Hamad, Jibran Sualeh Muhammad, Hema Unnikannan, Mawieh Hamad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2021-11-01
Schriftenreihe:FEBS Open Bio
Schlagworte:
breast cancer
c‐MYC
FTH1
G9a
iron metabolism
Online Zugang:https://doi.org/10.1002/2211-5463.13303
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