Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival

Increased expression of Yes-associated protein-1 (YAP1) was shown to correlate with reduced survival in breast cancer (BC) patients. However, the exact mechanism of YAP1 regulation in BC cells remains ambiguous. Genomic sequence search showed that the promoter region of the YAP1 gene contains CpG Is...

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Publicado en:Neoplasia
Main Authors: Muhammad, Jibran Sualeh, Guimei, Maha, Jayakumar, Manju Nidagodu, Shafarin, Jasmin, Janeeh, Aisha Saleh, AbuJabal, Rola, Eladl, Mohamed Ahmed, Ranade, Anu Vinod, Ali, Amjad, Hamad, Mawieh
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2020
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Original article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695929/
https://ncbi.nlm.nih.gov/pubmed/33242831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.11.002
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