Purine metabolism in bone marrow microenvironment inhibits hematopoietic stem cell differentiation under microgravity
Abstract Background Spaceflight and microgravity environments have been shown to cause significant health impairments, including bone loss, immune dysfunction, and hematopoietic disorders. Hematopoietic stem cells (HSCs), as progenitors of the hematopoietic system, are critical for the continuous re...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2025-03-01
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| Serie: | Stem Cell Research & Therapy |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s13287-025-04213-9 |
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