The spatiotemporal heterogeneity of the biophysical microenvironment during hematopoietic stem cell development: from embryo to adult

Abstract Hematopoietic stem cells (HSCs) with the ability to self-renew and differentiate are responsible for maintaining the supply of all types of blood cells. The complex and delicate microenvironment surrounding HSCs is called the HSC niche and can provide physical, chemical, and biological stim...

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Autores principales:	Guolin Shi, Pan Zhang, Xi Zhang, Jing Li, Xinmin Zheng, Jinxiao Yan, Nu Zhang, Hui Yang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-09-01
Colección:	Stem Cell Research & Therapy
Materias:	Spatiotemporal heterogeneity Biophysical microenvironment Hematopoietic stem cells Fate regulation
Acceso en línea:	https://doi.org/10.1186/s13287-023-03464-8
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