Nupr1 Negatively Regulates Endothelial to Hematopoietic Transition in the Aorta‐Gonad‐Mesonephros Region

Abstract In the aorta of mid‐gestational mouse embryos, a specialized endothelial subpopulation termed hemogenic endothelial cells (HECs) develops into hematopoietic stem and progenitor cells (HSPCs), through a conserved process of endothelial‐to‐hematopoietic transition (EHT). EHT is tightly contro...

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Detalhes bibliográficos

Principais autores:	Haizhen Wang, Di Liu, Haifeng Chen, Yuqing Jiao, Haixin Zhao, Zongcheng Li, Siyuan Hou, Yanli Ni, Rong Zhang, Jinyong Wang, Jie Zhou, Bing Liu, Yu Lan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-02-01
Colecção:	Advanced Science
Assuntos:	endothelial‐to‐hematopoietic transition hematopoietic stem cells hemogenic endothelial cells Nupr1 single‐cell RNA sequencing
Acesso em linha:	https://doi.org/10.1002/advs.202203813
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