Asc-dependent and independent mechanisms contribute to restriction of Legionella pneumophila infection in murine macrophages

The apoptosis-associated speck-like protein containing a caspase recruitment domain (Asc) is an adaptor molecule that mediates inflammatory and apoptotic signals. Legionella pneumophila (L. pneumophila) is an intracellular bacterium and the causative agent of Legionnaire’s pneumonia. L. pneumophila...

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Autors principals:	Amal O Amer, Dalia H.A. Abdelaziz, Mikhail A Gavrilin, Anwari eAkhter, Kyle eCaution, Sheetal eKotrange, Arwa eAbu Khweek, Basant A. Abdulrahman, Zeinab A. Hassan, Fathia Z. El-Sharkawi, Simranjit S. Bedi, Katherine eLadner, Mahmoud eMostafa, Andrea eDoseff, Elba M Gonzalez-Mejia, Dennis eGuttridge, Thirumala-Devi eKanneganti, Clay B. Marsh, Mark D. Wewers
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2011-02-01
Col·lecció:	Frontiers in Cellular and Infection Microbiology
Matèries:	Legionella pneumophila Inflammasome caspase-1 ASC
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00018/full
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