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Asc-dependent and independent mechanisms contribute to restriction of Legionella pneumophila infection in murine macrophages

The apoptosis-associated speck-like protein containing a caspase recruitment domain (Asc) is an adaptor molecule that mediates inflammatory and apoptotic signals. Legionella pneumophila (L. pneumophila) is an intracellular bacterium and the causative agent of Legionnaire’s pneumonia. L. pneumophila...

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Автори: Amal O Amer, Dalia H.A. Abdelaziz, Mikhail A Gavrilin, Anwari eAkhter, Kyle eCaution, Sheetal eKotrange, Arwa eAbu Khweek, Basant A. Abdulrahman, Zeinab A. Hassan, Fathia Z. El-Sharkawi, Simranjit S. Bedi, Katherine eLadner, Mahmoud eMostafa, Andrea eDoseff, Elba M Gonzalez-Mejia, Dennis eGuttridge, Thirumala-Devi eKanneganti, Clay B. Marsh, Mark D. Wewers
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2011-02-01
Серія:Frontiers in Cellular and Infection Microbiology
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Онлайн доступ:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00018/full
Теги: Додати тег
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