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Asc-dependent and independent mechanisms contribute to restriction of Legionella pneumophila infection in murine macrophages

The apoptosis-associated speck-like protein containing a caspase recruitment domain (Asc) is an adaptor molecule that mediates inflammatory and apoptotic signals. Legionella pneumophila (L. pneumophila) is an intracellular bacterium and the causative agent of Legionnaire’s pneumonia. L. pneumophila...

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Váldodahkkit: Amal O Amer, Dalia H.A. Abdelaziz, Mikhail A Gavrilin, Anwari eAkhter, Kyle eCaution, Sheetal eKotrange, Arwa eAbu Khweek, Basant A. Abdulrahman, Zeinab A. Hassan, Fathia Z. El-Sharkawi, Simranjit S. Bedi, Katherine eLadner, Mahmoud eMostafa, Andrea eDoseff, Elba M Gonzalez-Mejia, Dennis eGuttridge, Thirumala-Devi eKanneganti, Clay B. Marsh, Mark D. Wewers
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2011-02-01
Ráidu:Frontiers in Cellular and Infection Microbiology
Fáttát:
Liŋkkat:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00018/full
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