Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage.
The relationship of HIV tropism with disease progression and the recent development of CCR5-blocking drugs underscore the importance of monitoring virus coreceptor usage. As an alternative to costly phenotypic assays, computational methods aim at predicting virus tropism based on the sequence and st...
Guardado en:
| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2013-01-01
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| Colección: | PLoS Computational Biology |
| Acceso en línea: | http://europepmc.org/articles/PMC3605109?pdf=render |
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