CXCR4- and CCR5-Tropic HIV-1 Clones Are Both Tractable to Grow in Rhesus Macaques

A major issue for present HIV-1 research is to establish model systems that reflect or mimic viral replication and pathogenesis actually observed in infected humans. To this end, various strategies using macaques as infection targets have long been pursued. In particular, experimental infections of...

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Hlavní autoři:	Naoya Doi, Tomoyuki Miura, Hiromi Mori, Hiromi Sakawaki, Takaaki Koma, Akio Adachi, Masako Nomaguchi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-10-01
Edice:	Frontiers in Microbiology
Témata:	HIV-1 primate model rhesus macaque HIV-1rmt CXCR4-tropic CCR5-tropic
On-line přístup:	https://www.frontiersin.org/article/10.3389/fmicb.2018.02510/full
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