Unique profile of predominant CCR5-tropic in CRF07_BC HIV-1 infections and discovery of an unusual CXCR4-tropic strain

CRF07_BC is one of the most prevalent HIV-1 strains in China, which contributes over one-third of the virus transmissions in the country. In general, CRF07_BC is associated with slower disease progression, while the underlying mechanisms remain unclear. Our study focused on envelope proteins (Env) a...

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Hlavní autoři:	Xiaoyan Hu, Yi Feng, Kang Li, Yueyang Yu, Abdur Rashid, Hui Xing, Yuhua Ruan, Lingling Lu, Min Wei, Yiming Shao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-09-01
Edice:	Frontiers in Immunology
Témata:	HIV-1 CRF07_BC CXCR4 CCR5 tropism
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.911806/full
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