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Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage.

The relationship of HIV tropism with disease progression and the recent development of CCR5-blocking drugs underscore the importance of monitoring virus coreceptor usage. As an alternative to costly phenotypic assays, computational methods aim at predicting virus tropism based on the sequence and st...

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Váldodahkkit: Katarzyna Bozek, Thomas Lengauer, Saleta Sierra, Rolf Kaiser, Francisco S Domingues
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2013-01-01
Ráidu:PLoS Computational Biology
Liŋkkat:http://europepmc.org/articles/PMC3605109?pdf=render
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