Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno‐associated virus capsid and promoter

Abstract In this report, we describe the development of a modified adeno‐associated virus (AAV) capsid and promoter for transduction of retinal ON‐bipolar cells. The bipolar cells, which are post‐synaptic to the photoreceptors, are important retinal targets for both basic and preclinical research. I...

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מידע ביבליוגרפי

Principais autores:	Therese Cronin, Luk H Vandenberghe, Péter Hantz, Josephine Juttner, Andreas Reimann, Ágota–Enikő Kacsó, Rachel M Huckfeldt, Volker Busskamp, Hubertus Kohler, Pamela S Lagali, Botond Roska, Jean Bennett
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Springer Nature 2014-08-01
סדרה:	EMBO Molecular Medicine
נושאים:	adeno‐associated virus capsid library multi‐electrode array optogenetics promoter optimization
גישה מקוונת:	https://doi.org/10.15252/emmm.201404077
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!