Prion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegeneration.

Doppel protein (Dpl) is a paralog of the cellular form of the prion protein (PrP(C)), together sharing common structural and biochemical properties. Unlike PrP(C), which is abundantly expressed throughout the central nervous system (CNS), Dpl protein expression is not detectable in the CNS. Interest...

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Asıl Yazarlar:	Stefano Benvegnù, Diego Franciotta, Josh Sussman, Angela Bachi, Elisabetta Zardini, Paola Torreri, Cedric Govaerts, Salvatore Pizzo, Giuseppe Legname
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Public Library of Science (PLoS) 2009-06-01
Seri Bilgileri:	PLoS ONE
Online Erişim:	http://europepmc.org/articles/PMC2693666?pdf=render
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