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Absence of the prion protein homologue Doppel causes male sterility

The agent that causes prion diseases is thought to be identical with PrP(Sc), a conformer of the normal prion protein PrP(C). PrP(C)-deficient mice do not exhibit major pathologies, perhaps because they express a protein termed Dpl, which shares significant biochemical and structural homology with P...

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Autors principals: Behrens, Axel, Genoud, Nicolas, Naumann, Heike, Rülicke, Thomas, Janett, Fredi, Heppner, Frank L., Ledermann, Birgit, Aguzzi, Adriano
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125402/
https://ncbi.nlm.nih.gov/pubmed/12110578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf386
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