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Absence of the prion protein homologue Doppel causes male sterility
The agent that causes prion diseases is thought to be identical with PrP(Sc), a conformer of the normal prion protein PrP(C). PrP(C)-deficient mice do not exhibit major pathologies, perhaps because they express a protein termed Dpl, which shares significant biochemical and structural homology with P...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125402/ https://ncbi.nlm.nih.gov/pubmed/12110578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf386 |
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