Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC

Abstract Background Abnormal activation of NLRP3 inflammasome is related to a series of inflammatory diseases, including type 2 diabetes, gouty arthritis, non-alcoholic steatohepatitis (NASH), and neurodegenerative disorders. Therefore, targeting NLRP3 inflammasome is regarded as a potential therape...

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Xehetasun bibliografikoak

Egile Nagusiak:	Jia Zhao, Hongbin Liu, Zhixian Hong, Wei Luo, Wenqing Mu, Xiaorong Hou, Guang Xu, Zhie Fang, Lutong Ren, Tingting Liu, Jincai Wen, Wei Shi, Ziying Wei, Yongping Yang, Wenjun Zou, Jun Zhao, Xiaohe Xiao, Zhaofang Bai, Xiaoyan Zhan
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2023-07-01
Saila:	Molecular Medicine
Gaiak:	Tanshinone I NLRP3 inflammasome ASC LPS-induced septic shock NASH
Sarrera elektronikoa:	https://doi.org/10.1186/s10020-023-00671-0
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