Integrative transcriptomic and metabolomic analysis explores mechanisms by which Astragalus membranaceus and Salvia miltiorrhiza ameliorates hypertensive renal damage

Abstract To explore the mechanism by which Astragalus membranaceus and Salvia miltiorrhiza (AS) regulates the “metabolic- transcriptional” co-expression network to improve Hypertensive renal damage (HRD). Spontaneously hypertensive rats (SHRs) were used to establish the model of HRD. The structure a...

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Principais autores:	Wenpeng Liu, Cong Han, Wanli Xu, Yanyun Jiang, Yao Liu
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-09-01
Serija:	Scientific Reports
Teme:	Metabolomics Transcriptomic Hypertensive renal damage Astragalus membranaceus Salvia miltiorrhiza Mechanism
Online dostop:	https://doi.org/10.1038/s41598-025-18241-1
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