Integrative transcriptomic and metabolomic analysis explores mechanisms by which Astragalus membranaceus and Salvia miltiorrhiza ameliorates hypertensive renal damage

Abstract To explore the mechanism by which Astragalus membranaceus and Salvia miltiorrhiza (AS) regulates the “metabolic- transcriptional” co-expression network to improve Hypertensive renal damage (HRD). Spontaneously hypertensive rats (SHRs) were used to establish the model of HRD. The structure a...

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Autori principali:	Wenpeng Liu, Cong Han, Wanli Xu, Yanyun Jiang, Yao Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-09-01
Serie:	Scientific Reports
Soggetti:	Metabolomics Transcriptomic Hypertensive renal damage Astragalus membranaceus Salvia miltiorrhiza Mechanism
Accesso online:	https://doi.org/10.1038/s41598-025-18241-1
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