Integrative transcriptomic and metabolomic analysis explores mechanisms by which Astragalus membranaceus and Salvia miltiorrhiza ameliorates hypertensive renal damage

Abstract To explore the mechanism by which Astragalus membranaceus and Salvia miltiorrhiza (AS) regulates the “metabolic- transcriptional” co-expression network to improve Hypertensive renal damage (HRD). Spontaneously hypertensive rats (SHRs) were used to establish the model of HRD. The structure a...

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Detalhes bibliográficos

Principais autores:	Wenpeng Liu, Cong Han, Wanli Xu, Yanyun Jiang, Yao Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-09-01
coleção:	Scientific Reports
Assuntos:	Metabolomics Transcriptomic Hypertensive renal damage Astragalus membranaceus Salvia miltiorrhiza Mechanism
Acesso em linha:	https://doi.org/10.1038/s41598-025-18241-1
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