Integrative transcriptomic and metabolomic analysis explores mechanisms by which Astragalus membranaceus and Salvia miltiorrhiza ameliorates hypertensive renal damage

Abstract To explore the mechanism by which Astragalus membranaceus and Salvia miltiorrhiza (AS) regulates the “metabolic- transcriptional” co-expression network to improve Hypertensive renal damage (HRD). Spontaneously hypertensive rats (SHRs) were used to establish the model of HRD. The structure a...

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Главные авторы:	Wenpeng Liu, Cong Han, Wanli Xu, Yanyun Jiang, Yao Liu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2025-09-01
Серии:	Scientific Reports
Предметы:	Metabolomics Transcriptomic Hypertensive renal damage Astragalus membranaceus Salvia miltiorrhiza Mechanism
Online-ссылка:	https://doi.org/10.1038/s41598-025-18241-1
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