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FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways

Abstract Background Mutations in the receptor tyrosine kinase gene fibroblast growth factor receptor 2 (FGFR2) occur at a high frequency in endometrial cancer (EC) and have been linked to advanced and recurrent disease. However, little is known about how these mutations drive carcinogenesis. Methods...

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Detaylı Bibliyografya
Asıl Yazarlar: Garima Dixit, Jesus Gonzalez‐Bosquet, Joseph Skurski, Eric J. Devor, Erin B. Dickerson, Warren B. Nothnick, Priya D. Issuree, Kimberly K. Leslie, Thorsten Maretzky
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2023-05-01
Seri Bilgileri:Clinical and Translational Medicine
Konular:
Online Erişim:https://doi.org/10.1002/ctm2.1223
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