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Polystyrene nanoplastics carrying copper ion induce FDX1-mediated cuproptosis

Polystyrene nanoplastics (PS-NPs) and copper ions (Cu²⁺) are common environmental pollutants, yet their combined toxicological effects remain poorly understood. This study demonstrates that PS-NPs act as carriers of Cu²⁺, facilitating intracellular accumulation and inducing cuproptosis, a recently i...

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Principais autores: Huiqi Li, Qizhuan Lin, Huanpeng Liu, Zheyan Chen, Xueliang Zhang, Liyuan Jin, Renyi Peng, Huanzhi Jin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-09-01
Serier:Ecotoxicology and Environmental Safety
Fag:
polystyrene nanoplastics
Cu2+
Cuproptosis
FDX1
Zebrafish larvae
Hep G2
Online adgang:http://www.sciencedirect.com/science/article/pii/S0147651325012680
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