Cuproptosis Contributes to Cisplatin-Induced Nephrotoxicity: Insights into Thymol’s Potential Inhibitory and Protective Effects

<b>Background:</b> Cisplatin is a powerful treatment for cancer; however, its clinical application is compromised due to its potential for nephrotoxicity. The development of nephroprotective agents is hindered mainly due to the lack of understanding of the exact underlying mechanism. Additionally, t...

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Autori principali:	Layla A. Al-Kharashi, Amira M. Badr, Reem T. Atawia, Elshaymaa I. Elmongy, Hanan Henidi, Rehab Ali, Awatif A. Binmughram, Lian Al-Abkka, Nervana Mostafa Kamal Bayoumy, Yasmen F. Mahran
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-11-01
Serie:	Pharmaceuticals
Soggetti:	acute nephrotoxicity cisplatin thymol cuproptosis DLAT FDX1
Accesso online:	https://www.mdpi.com/1424-8247/18/11/1686
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