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Thymol Preserves Spermatogenesis and Androgen Production in Cisplatin-Induced Testicular Toxicity by Modulating Ferritinophagy, Oxidative Stress, and the Keap1/Nrf2/HO-1 Pathway

Cisplatin (CDDP) is a widely used chemotherapeutic agent, but its off-target toxicity, including testicular damage, limits clinical use. Bioactive compounds may help mitigate chemotherapy-induced reproductive toxicity. This study investigates thymol’s role in modulating ferritinophagy to preserve re...

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Váldodahkkit: Amira M. Badr, Sheka Aloyouni, Yasmin Mahran, Hanan Henidi, Elshaymaa I. Elmongy, Haya M. Alsharif, Aliyah Almomen, Sahar Soliman
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2025-09-01
Ráidu:Biomolecules
Fáttát:
Liŋkkat:https://www.mdpi.com/2218-273X/15/9/1277
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