Molecular determinants of allosteric modulation of protein disulfide isomerase by small-molecule b′-ligands
Allosteric modulation is central to enzyme function and an attractive strategy for drug development. Protein Disulfide Isomerase (PDI), the prototypical thiol-isomerase, exemplifies this potential through its structural flexibility and involvement in neurodegeneration, cancer, and thromboinflammator...
Guardat en:
| Autors principals: | , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2026-03-01
|
| Col·lecció: | Redox Biology |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S221323172600042X |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|