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TCA cycle-derived oncometabolites in cancer and the immune microenvironment

Abstract Oncometabolites are aberrant metabolic byproducts that arise from mutations in enzymes of the tricarboxylic acid (TCA) cycle or related metabolic pathways and play central roles in tumor progression and immune evasion. Among these, 2-hydroxyglutarate (2-HG), succinate, and fumarate are the...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Shukla Sarkar, Chien-I Chang, Jussekia Jean, Meng-Ju Wu
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2025-09-01
Sraith:Journal of Biomedical Science
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12929-025-01186-y
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