TCA cycle-derived oncometabolites in cancer and the immune microenvironment
Abstract Oncometabolites are aberrant metabolic byproducts that arise from mutations in enzymes of the tricarboxylic acid (TCA) cycle or related metabolic pathways and play central roles in tumor progression and immune evasion. Among these, 2-hydroxyglutarate (2-HG), succinate, and fumarate are the...
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| Principais autores: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BMC
2025-09-01
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| 叢編: | Journal of Biomedical Science |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1186/s12929-025-01186-y |
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