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Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs

Abstract Background Microbial infections, particularly those caused by rhinovirus (RV) and respiratory syncytial virus (RSV), are major triggers for asthma exacerbations. These viruses activate toll-like receptors (TLRs), initiating an innate immune response. To better understand microbial-induced a...

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Hoofdauteurs: Yujiao Xiang, Jielu Liu, Mu Nie, Gunnar Nilsson, Jesper Säfholm, Mikael Adner
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2024-11-01
Reeks:Respiratory Research
Onderwerpen:
Respiratory infections
Poly (I:C)
Lipopolysaccharide (LPS)
Imiquimod
Inflammation
Mast cell
Online toegang:https://doi.org/10.1186/s12931-024-03050-3
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