Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs

Abstract Background Microbial infections, particularly those caused by rhinovirus (RV) and respiratory syncytial virus (RSV), are major triggers for asthma exacerbations. These viruses activate toll-like receptors (TLRs), initiating an innate immune response. To better understand microbial-induced a...

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Главные авторы:	Yujiao Xiang, Jielu Liu, Mu Nie, Gunnar Nilsson, Jesper Säfholm, Mikael Adner
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2024-11-01
Серии:	Respiratory Research
Предметы:	Respiratory infections Poly (I:C) Lipopolysaccharide (LPS) Imiquimod Inflammation Mast cell
Online-ссылка:	https://doi.org/10.1186/s12931-024-03050-3
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