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Wnt-3a Induces Cytokine Release in Human Mast Cells

Mast cells are well known for their detrimental effects in allergies and asthma, and Wnt signaling has recently been implicated in asthma and other airway diseases. However, it is not known if or how Wnts affect human mast cells. Since Wnt expression is elevated in individuals with asthma and is lin...

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Principais autores: Julia Tebroke, Joris E. Lieverse, Jesper Säfholm, Gunnar Schulte, Gunnar Nilsson, Elin Rönnberg
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-11-01
Serier:Cells
Fag:
mast cells
wnt signaling
wnt-3a
frizzled
il-8
ccl8
asthma
Online adgang:https://www.mdpi.com/2073-4409/8/11/1372
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