Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

Due to continuous antigenic drift and occasional antigenic shift, influenza viruses escape from human adaptive immunity resulting in significant morbidity and mortality in humans. Therefore, to avoid the need for annual reformulation and readministration of seasonal influenza virus vaccines, we are...

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Ngā kaituhi matua:	Wen-Chun Liu, Raffael Nachbagauer, Daniel Stadlbauer, Alicia Solórzano, Francesco Berlanda-Scorza, Adolfo García-Sastre, Peter Palese, Florian Krammer, Randy A. Albrecht
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2019-04-01
Rangatū:	Frontiers in Immunology
Ngā marau:	universal influenza virus vaccine live-attenuated influenza vaccine ferret stalk antibody chimeric hemagglutinin heterosubtypic protection
Urunga tuihono:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00756/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!