Interferon-stimulated gene TDRD7 interacts with AMPK and inhibits its activation to suppress viral replication and pathogenesis

ABSTRACT Many viruses activate cellular autophagy in infected cells to facilitate their replication. Recently, we identified an interferon (IFN)-stimulated gene (ISG) Tudor domain containing 7 (TDRD7), which inhibits viral replication by blocking autophagy pathway. Here, we present a molecular mecha...

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Detalhes bibliográficos

Principais autores:	Sukanya Chakravarty, Gayatri Subramanian, Sonam Popli, Manoj Veleeparambil, Shumin Fan, Ritu Chakravarti, Saurabh Chattopadhyay
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2023-10-01
coleção:	mBio
Assuntos:	Innate immunity interferon ISGs TDRD7 AMPK autophagy
Acesso em linha:	https://journals.asm.org/doi/10.1128/mbio.00611-23
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