Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent <i>IFNB1</i> Expression

The type I interferon (IFN) response is a principal component of our immune system that allows to counter a viral attack immediately upon viral entry into host cells. Upon engagement of aberrantly localised nucleic acids, germline-encoded pattern recognition receptors convey their find via a signall...

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Bibliografische Detailangaben

Hauptverfasser:	Hella Schwanke, Markus Stempel, Melanie M. Brinkmann
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-07-01
Schriftenreihe:	Viruses
Schlagworte:	interferon regulatory factor IRF3 innate immunity antiviral response immune modulation viral evasion
Online-Zugang:	https://www.mdpi.com/1999-4915/12/7/733
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