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Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent <i>IFNB1</i> Expression

The type I interferon (IFN) response is a principal component of our immune system that allows to counter a viral attack immediately upon viral entry into host cells. Upon engagement of aberrantly localised nucleic acids, germline-encoded pattern recognition receptors convey their find via a signall...

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Principais autores: Hella Schwanke, Markus Stempel, Melanie M. Brinkmann
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-07-01
Serier:Viruses
Fag:
interferon regulatory factor
IRF3
innate immunity
antiviral response
immune modulation
viral evasion
Online adgang:https://www.mdpi.com/1999-4915/12/7/733
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