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Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells

Summary: Loss of cone photoreceptors, crucial for daylight vision, has the greatest impact on sight in retinal degeneration. Transplantation of stem cell-derived L/M-opsin cones, which form 90% of the human cone population, could provide a feasible therapy to restore vision. However, transcriptomic...

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Principais autores: Emily Welby, Jorn Lakowski, Valentina Di Foggia, Dimitri Budinger, Anai Gonzalez-Cordero, Aaron T.L. Lun, Michael Epstein, Aara Patel, Elisa Cuevas, Kamil Kruczek, Arifa Naeem, Federico Minneci, Mike Hubank, David T. Jones, John C. Marioni, Robin R. Ali, Jane C. Sowden
格式: Artigo
語言:Inglês
出版: Elsevier 2017-12-01
叢編:Stem Cell Reports
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2213671117304733
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