QR-koodi

Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia

Abstract Background Mixed lineage leukemia (MLL) gene translocations are found in ~75 % infant and 10 % adult acute leukemia, showing a poor prognosis. Lysine-specific demethylase 1 (LSD1) has recently been implicated to be a drug target for this subtype of leukemia. More studies using potent LSD1 i...

Täydet tiedot

Tallennettuna:
Päätekijät: Zizhen Feng, Yuan Yao, Chao Zhou, Fengju Chen, Fangrui Wu, Liping Wei, Wei Liu, Shuo Dong, Michele Redell, Qianxing Mo, Yongcheng Song
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2016-03-01
Sarja:Journal of Hematology & Oncology
Aiheet:
MLL-rearranged leukemia
Lysine-specific demethylase 1
Enzyme inhibitor
Drug discovery
Leukemia therapeutics
Linkit:http://link.springer.com/article/10.1186/s13045-016-0252-7
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia