Inhibition of fibrin polymerization by synthetic peptides corresponding to Аα195-205 and γ69-77 sites of fibrin molecule

Using the idea of “proline brackets” we have found four sites in fibrin amino acid sequence, and appropriate peptides were synthesized: γ69NPDESSKPN77, Bβ228QPDSSVKPY236, Bβ455RPFFPQ460 and Aα195LPSRDRQHLPL205. Turbidity and electron-microscopy analyses have demonstrated that synthetic peptide Аα195...

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Үндсэн зохиолчид:	T. A. Pozniak, L. P. Urvant, P. G. Gritsenko, V. I. Chernishov, N. A. Pydiura, E. V. Lugovskoi, S. V. Komisarenko
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2014-08-01
Цуврал:	The Ukrainian Biochemical Journal
Нөхцлүүд:	inhibitors peptides proline brackets sites of fibrin polymerization
Онлайн хандалт:	http://ukrbiochemjournal.org/wp-content/uploads/2015/06/Pozniak_4_14.pdf
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!