USAGE OF MONOCLONAL ANTIBODIES FOR DETERMINATION OF LOCALIZATION OF ANTIGENIC DETERMINANTS AND FIBRIN POLYMERIZATION SITES WITHIN FIBRINOGEN AND FIBRIN MOLECULES AND THEIR APPLICATION IN TEST--SYSTEMS FOR DIAGNOSTICS AND THE THREAT OF THROMBUS FORMATION

It was shown by monoclonal antibodies that B?N-region of fibrin desA molecule (B?1-53) comprises the polymerization site including the peptide bond B?14-15. This site participates in the second stage of fibrin polymerization — lateral association of protofibrils. In the B?15-53 fragment was also fou...

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Autors principals:	E. V. Lugovskoi, I. N. Kolesnikova, S. V. Komisarenko
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2013-08-01
Col·lecció:	Biotechnologia Acta
Matèries:	fibrinogen fibrin monoclonal antibodies thrombosis diagnostic test systems.
Accés en línia:	http://biotechnology.kiev.ua/images/no4_2013/lugovskoy_4_2013.pdf
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