The C291R Tau Variant Forms Different Types of Protofibrils
Mutations in the MAPT gene can lead to disease-associated variants of tau. However, the pathological mechanisms behind these genetic tauopathies are poorly understood. Here, we characterized the aggregation stages and conformational changes of tau C291R, a recently described MAPT mutation with poten...
Sábháilte in:
| Príomhchruthaitheoirí: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Frontiers Media S.A.
2020-03-01
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| Sraith: | Frontiers in Molecular Neuroscience |
| Ábhair: | |
| Rochtain ar líne: | https://www.frontiersin.org/article/10.3389/fnmol.2020.00039/full |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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