The C291R Tau Variant Forms Different Types of Protofibrils
Mutations in the MAPT gene can lead to disease-associated variants of tau. However, the pathological mechanisms behind these genetic tauopathies are poorly understood. Here, we characterized the aggregation stages and conformational changes of tau C291R, a recently described MAPT mutation with poten...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020-03-01
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| coleção: | Frontiers in Molecular Neuroscience |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/article/10.3389/fnmol.2020.00039/full |
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