RECON-Dependent Inflammation in Hepatocytes Enhances <named-content content-type="genus-species">Listeria monocytogenes</named-content> Cell-to-Cell Spread

ABSTRACT The oxidoreductase RECON is a high-affinity cytosolic sensor of bacterium-derived cyclic dinucleotides (CDNs). CDN binding inhibits RECON’s enzymatic activity and subsequently promotes inflammation. In this study, we sought to characterize the effects of RECON on the infection cycle of the...

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Principais autores:	Adelle P. McFarland, Thomas P. Burke, Alexie A. Carletti, Rochelle C. Glover, Hannah Tabakh, Matthew D. Welch, Joshua J. Woodward
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2018-07-01
Series:	mBio
Assuntos:	CDNs Listeria monocytogenes NF-κB RECON actin-based motility cyclic di-AMP
Acceso en liña:	https://journals.asm.org/doi/10.1128/mBio.00526-18
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