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Ranking mAb–excipient interactions in biologics formulations by NMR spectroscopy and computational approaches

Excipients are added to biopharmaceutical formulations to enhance protein stability and enable the development of robust formulations with acceptable physicochemical properties, but the mechanism by which they confer stability is not fully understood. Here, we aimed to elucidate the mechanism throug...

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書誌詳細
主要な著者: Chunting Zhang, Steven T. Gossert, Jonathan Williams, Michael Little, Marilia Barros, Barton Dear, Bradley Falk, Ankit D. Kanthe, Robert Garmise, Luciano Mueller, Andrew Ilott, Anuji Abraham
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis Group 2023-12-01
シリーズ:mAbs
主題:
オンライン・アクセス:https://www.tandfonline.com/doi/10.1080/19420862.2023.2212416
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