A Cancer-Specific Anti-Podocalyxin Monoclonal Antibody (humPcMab-60) Demonstrated Antitumor Efficacy in Pancreatic and Colorectal Cancer Xenograft Models

<b>Background</b>: Podocalyxin (PODXL) has been identified as a promising therapeutic target and a potential diagnostic biomarker in various tumors. Despite the therapeutic potential of anti-PODXL monoclonal antibodies (mAbs), their further development has been limited by concerns regarding potentia...

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Autors principals:	Hiroyuki Suzuki, Tomokazu Ohishi, Takuro Nakamura, Miyuki Yanaka, Saori Handa, Tomohiro Tanaka, Mika K. Kaneko, Yukinari Kato
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-08-01
Col·lecció:	Antibodies
Matèries:	podocalyxin cancer-specific monoclonal antibody antibody-dependent cellular cytotoxicity complement-dependent cellular cytotoxicity human cancer xenograft
Accés en línia:	https://www.mdpi.com/2073-4468/14/3/67
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