How Do mAbs Make Use of Complement to Kill Cancer Cells? The Role of Ca²⁺

We examined the kinetics and mechanisms by which monoclonal antibodies (mAbs) utilize complement to rapidly kill targeted cancer cells. Based on results from flow cytometry, confocal microscopy and high-resolution digital imaging experiments, the general patterns which have emerged reveal cytotoxic...

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Hlavní autoři:	Ronald P. Taylor, Margaret A. Lindorfer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-09-01
Edice:	Antibodies
Témata:	complement therapeutic monoclonal antibodies (mAbs) Ca<sup>2+</sup> fluorescence microscopy
On-line přístup:	https://www.mdpi.com/2073-4468/9/3/45
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