Spatialsmooth: a spatially-aware convolutional autoencoder framework for enhanced deconvolution of spatial transcriptomics data

Abstract Spatial transcriptomics technologies have revolutionized our understanding of tissue heterogeneity by providing gene expression data with spatial context. However, due to the limited resolution of some of these techniques, multiple cell types are often captured at each spatial location. Sev...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Xiao Yang, Jinjin Xiang, Yanbin Feng, Yanfang Zhao, Huamei Li, Xiaozhou Chen
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2025-09-01
Σειρά:	BMC Genomics
Θέματα:	Spatial transcriptomics Deconvolution Convolutional autoencoder Positional encoding
Διαθέσιμο Online:	https://doi.org/10.1186/s12864-025-11959-2
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