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A Bayesian hierarchical model with spatially varying dispersion for reference-free cell type deconvolution in spatial transcriptomics

A major challenge in spatial transcriptomics (ST) is resolving cellular composition, especially in technologies lacking single-cell resolution. The mixture of transcriptional signals within spatial spots complicates deconvolution and downstream analyses. To uncover the spatial heterogeneity of tissu...

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Bibliografiska uppgifter
Huvudupphov: Xuan Li, Yincai Tang, Jingsi Ming, Xingjie Shi
Materialtyp: Artigo
Språk:Inglês
Utgiven: Taylor & Francis Group 2025-04-01
Serie:Statistical Theory and Related Fields
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Länkar:https://www.tandfonline.com/doi/10.1080/24754269.2025.2495651
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