Spatialsmooth: a spatially-aware convolutional autoencoder framework for enhanced deconvolution of spatial transcriptomics data

Abstract Spatial transcriptomics technologies have revolutionized our understanding of tissue heterogeneity by providing gene expression data with spatial context. However, due to the limited resolution of some of these techniques, multiple cell types are often captured at each spatial location. Sev...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Xiao Yang, Jinjin Xiang, Yanbin Feng, Yanfang Zhao, Huamei Li, Xiaozhou Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-09-01
coleção:	BMC Genomics
Assuntos:	Spatial transcriptomics Deconvolution Convolutional autoencoder Positional encoding
Acesso em linha:	https://doi.org/10.1186/s12864-025-11959-2
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!