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Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase

<p>Abstract</p> <p>Background</p> <p>Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM i...

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Váldodahkkit: Paric Enesa, Schawalder James, Neff Norma F
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2003-10-01
Ráidu:BMC Cell Biology
Liŋkkat:http://www.biomedcentral.com/1471-2121/4/15
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