Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase
<p>Abstract</p> <p>Background</p> <p>Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM i...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2003-10-01
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| Serier: | BMC Cell Biology |
| Online adgang: | http://www.biomedcentral.com/1471-2121/4/15 |
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